| Saumithraಸೌಮೀತ್ರಾ | Lord Lakshman son of Sumitra) |
| Sauvarಸೌವಾರ | Belonging to sound, A musical note |
| Savantಸವಂತ | A learned and wise scholar. |
| Savya Sachiಸಾವ್ಯ-ಸಾಚೀ | Another name of Arjun, Ambidextrous |
| Savyamoonthಸವಯಮೂನತಃ | Savyamoonth comes from An Indian word meaning, Defender of people |
| Savyashacheeಸವ್ಯಸಾಚೀ | Ambidextrous while shooting |
| Sayshanthಸಯಶಾಂತ | Avatar of Lord Vishnu, Good peace |
| Selva Kumarಸೇಲವಾ ಕುಮಾರ | A wealthy and prosperous young prince. |
| Selvanathnಸೇಲ್ವನಾಥಂ | Selvanathn means 'Gift of the Lord' or 'Divine Gift' in Sanskrit, a combination of Selva (Lord) and Nathn (Gift). |
| Selvianಸೇಲ್ವಿಯನ | Of or pertaining to Selvians, a people or tribe, possibly from the Latin 'selvus' meaning wild or savage. |
| Senaanyಸೇನಾನೀ | One of the kauravas |
| Senthil Kumarಸೇಂತೀಲ ಕುಮಾರ | Lord Murugan, Always youth |
| Serasಸೇರಸ | Derived from the Latin word 'serere,' meaning to sow or plant, often associated with fertility. |
| Seshanandಸೇಶಾನಂದ | Lord Vishnu, Beloved of sesh |
| Sesuಸೇಸು | Snake, Venkateswara |
| Sethu Lakshmiಸೇತು ಲಕ್ಷ್ಮೀ | Goddess Lakshmi, Worth |
| Setukruteಸೇತುಕೃತೇ | Builder of the bridge over ocean |
| Sewinಸೇವೀನ | Sewin is a Welsh name meaning 'little river' or 'stream', derived from the Old Welsh word 'sawyn'. |
| Shaantivಶಾಂತಿವ | One who is peaceful and calm in nature. |
| Shaastಶಾಸ್ತ | Ruler, One who commands |
| Shaastiಶಾಸ್ತೀ | Command, Royal authority, Hymn, Lord Murugan, Another name for Durga |
| Shabastಶಾಬಸ್ತ | Armoured, Protected |
| Shadanananಶಾದನಾನನ | Lord Subramanyan |
| Shagdavಶಾಗ್ದವ | Shagdav is a Mongolian name meaning 'bringer of good fortune' or 'auspicious one'. |
| Shailajಶೈಲಜ | Daughter of the mountains |
| Shaininಶೈನೀನ | Peaceful, Restrained |
| Shajaneeshಶಾಜನೀಶ | Shajaneesh is a Sanskrit name meaning 'Victory of the Lord' or 'Triumphant Lord'. |
| Shajunanಶಾಜುನಾನ | Shajunan is a variant of the name Shahjahan, meaning 'world conqueror' or 'conqueror of the world'. |
| Shakithಶಕಿತ | Shakith is a variant of Shakitha, meaning 'blessed' or 'fortunate' in Sanskrit, derived from the word 'shak' meaning 'good fortune'. |
| Shakthidharಶಕ್ತೀಧರ | Lord Shiva, The Lord Subramanian |
| Shakunthಶಾಕುನ್ತ | Derived from a bird, meaning auspicious. |
| Shakyaಶಕ್ಯ | Lord Buddha, Energy circle or a form of chakra |
| Shalivahanಶಾಲಿವಾಹನ | Name of a famous king |
| Hari Priyaಹರೀಪ್ರಿಯಾ | Goddess Lakshmi, Beloved of Hari |
| Shamathಶಾಮತ | Quiet, Tranquillity, A counseller, Residing in peace, Peaceful, Calm |
| Shamenಶಾಮೇನ | Holy Man, Happy, Auspicious, Security, Wealthy |
| Shamijithಶಮಿಜೀತ | Shamijith means 'peaceful victory' or 'victory of peace' in Malayalam, a language spoken in southern India. |
| Shammadಶಾಮ್ಮದ | One who has conquered his ego |
| Shampakಶಮ್ಪಕ | Created by thunderbolts, Brilliant |
| Shamvatಶಂವತ | Auspicious, Wealthy |